Switching From Dexilant to Nexium: Why, When, and How, a Guide

A woman showing discomfort due to acid refulx. Dexilant and Nexium both tackle GERD

If you’re considering switching from Dexilant to Nexium, then we have the ultimate guide below that explains everything you need to know.

As care providers of medications via our medication access service, we are well-positioned to help you understand the process of switching from Dexilant to Nexium and all the factors around it.

Let’s start with a quick summary, then we’ll get into more detail…

Dexilant and Nexium are GERD medications. Dexilant’s dual-release treats acid reflux. Nexium is availabel in both immeidate and delayed release. To switch, consult a doctor, adjust doses gradually, monitor symptoms, and consider the cost. Other Dexilant alternatives include Prilosec, and Prevacid.

That’s a quick assessment, but there is more to understand on this topic. So let’s go through the essentials.

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Gastroesophageal reflux disease (GERD) affects millions of individuals, causing discomfort and potential damage to the esophagus due to stomach acid flowing back into it.

Medications like Dexilant and Nexium belong to a class known as proton pump inhibitors (PPIs), commonly used to manage GERD symptoms.

This article explains the characteristics of Dexilant and Nexium, their potential interchangeability, and the key factors to consider when switching from Dexilant to Nexium.

switching from dexilant to nexium
A gentleman suffering from acid reflux, which may be helped by switching from Dexilant to Nexium

Switching from Dexilant to Nexium

To begin with, it helps to provide an overview of what each of these medications is, and how they tackle GERD. This will then help us to understand the process of switching from Dexilant to Nexium…

What is Dexilant

Dexilant is a brand name for dexlansoprazole, a PPI that works by suppressing the secretion of stomach acid. It is approved for the treatment of GERD, erosive esophagitis, and certain stomach conditions.

Dexilant is unique in that it contains two different types of granules that release medication at different times.

One set of granules releases the medication immediately, providing fast relief, while the other set releases the medication gradually, providing long-lasting effects.

This dual-release mechanism aims to provide consistent acid suppression throughout the day, effectively managing GERD symptoms and promoting the healing of the esophagus.

What is Nexium

Nexium, a generic name for esomeprazole, is another widely prescribed PPI.

Like Dexilant, Nexium reduces stomach acid production, relieving symptoms associated with GERD, erosive esophagitis, and peptic ulcers.

Nexium is known for its effectiveness and is available in both immediate-release and delayed-release forms.

It’s a potent inhibitor of acid production and is used for short-term and long-term management of various acid-related disorders.

So as both medications appear to perform similar functions, why would a patient consider switching from Dexilant to Nexium?

A woman showing discomfort due to acid reflux. Dexilant and Nexium both tackle GERD
A woman showing discomfort due to acid reflux. Dexilant and Nexium both tackle GERD

Circumstances for switching from Dexilant to Nexium

Switching between PPIs like Dexilant and Nexium can be a consideration based on individual circumstances. Every case is different, and different medications suit differing patient needs.

However, any medication switch should be made under the guidance of a healthcare professional, as they can assess the patient’s specific needs and health conditions.

Here’s a general overview of the process:

Consultation

Before considering a switch, consult a healthcare provider. They will evaluate your medical history, symptoms, and the reasons for the switch. Not everyone may need to switch, and alternatives might also be discussed.

Dosage Equivalency

Dexilant and Nexium have different dosages and release mechanisms. Your doctor will determine the appropriate Nexium dosage that aligns with your current Dexilant treatment, ensuring a smooth transition.

Gradual Transition

Abruptly stopping Dexilant and starting Nexium can lead to a rebound effect, where acid production may increase temporarily. Therefore, the transition is usually gradual, with a period of overlap to minimize potential disruptions in symptom control.

Monitoring

During the transition, close monitoring of your symptoms is essential. Your doctor may adjust the dosage if needed, based on your response to Nexium.

Who should consider switching from Dexilant to Nexium?

The decision to switch from Dexilant to Nexium should only be made in collaboration with a healthcare provider.

Individuals who might consider switching include those:

  • Experiencing inadequate symptom relief with Dexilant.
  • Experiencing side effects from Dexilant.
  • Patients who are experiencing symptom changes while taking Dexilant
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Considerations and concerns

Several factors should be considered when contemplating a switch between Dexilant and Nexium:

Effectiveness

Both medications are effective in managing GERD, but individual responses can vary. Switching may not necessarily lead to better symptom relief.

Cost

Nexium is often available under Prescription Hope’s medication access service. All the program requires initially is a simple enrollment process.

This route can be far more cost-effective for many patients, obtaining medications for as little as just $60.00 per month per medication through Prescription Hope’s medication access service.

Health conditions

Existing health conditions, medication interactions, and allergies should be considered before switching. Your healthcare advisor can assist with this assessment.

Dosage adjustment

The dosages of Dexilant and Nexium are not directly interchangeable. Should switching from Dexilant to Nexium be deemed appropriate, a healthcare provider will calculate an appropriate Nexium dose based on your current Dexilant dosage.

Rebound effect

We alluded to the potential of the rebound effect earlier in the article. Switching PPIs should be done gradually to avoid a rebound increase in acid production.

Consultation

Never switch medications without consulting a healthcare professional. They can guide you through the process and address any concerns. Remember also to enroll in our medication access service here.

If you also suffer from asthma, then read more about the connection between acid reflux and asthma here.

Now let’s look at when to switch…

image shows a selection of tablets and medications are available as alternatives to Dexilant available
image shows a selection of tablets and medications available as alternatives to Dexilant available

When to switch

Switching from Dexilant to Nexium might be considered if Dexilant is not providing sufficient symptom relief, if side effects are problematic, or if cost is a concern.

Timing can vary, but it’s typically discussed during a doctor’s visit when adjustments to treatment are being evaluated.

There is no specific time frame that is adhered to, as patients are considered on the merits of their condition.

Alternative medications to consider instead of Dexilant.

Aside from Nexium, there are some alternative medications to consider for the treatment of gastroesophageal reflux disease (GERD) or related conditions instead of Dexilant.

It’s important to consult with a healthcare provider to determine the most suitable option based on your specific needs and medical history. Here are some alternative medications to research further:

Prilosec (Omeprazole)

Omeprazole is another common PPI that decreases stomach acid production. It targets not the frequency of reflux episodes but limits acid reflux to reduce the harm it causes.

Prevacid (Lansoprazole)

Lansoprazole is another PPI used to treat GERD and related conditions. It helps reduce stomach acid and is available in various forms, including delayed-release capsules and orally disintegrating tablets.

Protonix (Pantoprazole)

Pantoprazole is a PPI that works to reduce stomach acid production. It’s available in both oral and intravenous formulations and is used to treat GERD, erosive esophagitis, and other acid-related conditions.

Aciphex (Rabeprazole)

Rabeprazole is a PPI that can be prescribed for GERD and certain stomach ulcers. It helps decrease acid production and promote healing in the esophagus.

Antacids

While not as potent as PPIs, antacids like Tums, Maalox, and Mylanta can provide temporary relief by neutralizing stomach acid. They are available over the counter and can be used for mild symptoms. You might also want to read more here about taking medications like this while pregnant.

Lifestyle Modifications

In addition to medications, lifestyle changes such as dietary adjustments, weight management, elevating the head of the bed, and avoiding trigger foods can help manage GERD symptoms.

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Switching from Dexilant to Nexium – Next steps

We hope this has answered your questions regarding switching from Dexilant to Nexium. Remember, to obtain these medications, potentially for just $60.00 per medication per month, be sure to enroll in our medication access service.

To conclude then, it’s important to remember that while these alternatives can be effective in managing GERD, individual responses may vary.

Consulting with a healthcare provider is crucial to determine the most appropriate medication or treatment plan based on your specific needs, medical history, and any existing health conditions.

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