Key Takeaways
- Fasenra (benralizumab) is a high-priced biologic injection, and its yearly cost depends on how many doses your treatment schedule requires.
- Savings offers for people with commercial insurance are only one option, and people without coverage have other ways to lower what they pay.
- If you qualify, you may get help with the cost of Fasenra, and a prescription advocacy service can handle the paperwork and renewals for you.
Fasenra (benralizumab) is a brand-name biologic injection used to treat severe eosinophilic asthma and a rarer condition called eosinophilic granulomatosis with polyangiitis (EGPA). For people paying cash, the Fasenra cost without insurance starts with a list price of $6,022.46 for each 30 mg dose.
That price repeats with every injection, so the yearly total reaches tens of thousands of dollars. Each pharmacy also sets its own cash price, so the amount you pay can vary from one to the next.
The same bill can reach insured patients when their medication isn’t covered by the plan. In this article, we’ll break down how the cost adds up over a year, what changes the price you pay, and how to afford Fasenra if you’re uninsured.
The Yearly Fasenra Cost Without Insurance by Treatment
At list price, a year of Fasenra for an adult runs from about $36,000 to more than $78,000, depending on the condition and the year of treatment. The list price is $6,022.46 for the 30 mg dose and $2,007.49 for the 10 mg dose, as of January 2026.
Fasenra is a biologic produced from living cells, which is part of why biologic drugs cost more.
Most patients use the 30 mg dose. The 10 mg dose is for children ages 6 to 11 who weigh less than 77 pounds.
Because Fasenra is given on a set schedule, the price of one dose is only the starting point. The number of doses you need each year decides the real total.
How Often Each Treatment Needs a Dose
The first year of treatment costs the most because it includes extra doses. The FDA-approved prescribing information sets the severe asthma schedule at 30 mg every 4 weeks for the first three doses, then every 8 weeks after that.
For EGPA, the schedule stays at one dose every 4 weeks, so the yearly total is much higher.
| Treatment Schedule | Doses per Year | Cost at List Price |
|---|---|---|
| Severe asthma, 30 mg, first year | 8 | $48,179.68 |
| Severe asthma, 30 mg, later years | 6 to 7 | $36,134.76 to $42,157.22 |
| EGPA, 30 mg, every 4 weeks | 13 | $78,291.98 |
| Children under 77 pounds, 10 mg, first year | 8 | $16,059.92 |
What Else Changes the Price You Pay
The manufacturer sets the list price, but the final bill can be higher. Two details decide how much gets added on top of it:
- Where you get the injection: A doctor’s office may bill for the visit and for giving the shot, while the Fasenra Pen can be used at home after training.
- The pharmacy: Fasenra may need to come from a specialty pharmacy, and the cash price depends on the pharmacy you use.
Before a dose is filled, ask the pharmacy for a cash quote on your exact strength. That quote gives you a real number to plan around.
How to Afford Fasenra When You Don’t Have Insurance
The manufacturer’s $0 copay offer is built for people with commercial insurance, usually through an employer. AstraZeneca’s terms require that coverage, so people who pay cash or are enrolled in a government-funded program need a different route.
If a commercial plan refuses to cover Fasenra even after an appeal, the manufacturer has a separate program for denied patients. For people with no coverage at all, each option below fits a different situation.
| Option | Who It’s For | What You Pay | What You Handle |
|---|---|---|---|
| Manufacturer copay offer | People with commercial insurance | As little as $0 per injection, up to $13,000 a year in help | Enrolling and using it with your plan |
| Manufacturer help for the uninsured | People without insurance who meet income guidelines | The medication is provided at no cost if you qualify | The application, doctor forms, and yearly renewal |
| Prescription Hope | People who qualify for manufacturer help and want the process managed | $70/month per medication | A short application, while the team handles the rest |
How Prescription Hope Handles the Process for You
Paying more than $6,000 per dose out of pocket is hard to keep up with over a year of treatment. For people who qualify, Prescription Hope replaces that bill with a flat $70/month per medication and takes care of the paperwork for you.
It is a prescription advocacy service, and it is not insurance, not a pharmacy, and not a coupon or discount card.
The team handles the manufacturer’s application, the forms with your doctor, and the yearly renewals, so you can get help paying for Fasenra without managing each step alone.
If you qualify, the medication itself is provided at no cost by the manufacturer.
Eligibility depends on household income, and the process follows a clear order:
- Enrollment: You complete a short application online.
- Welcome call: An enrollment specialist reviews your details and next steps with you.
- Doctor coordination: The team works with your doctor’s office on the required forms.
- Delivery and refills: After approval, Fasenra arrives at your home or your doctor’s office in 2 to 4 weeks, and the team keeps your prescription assistance going with each refill and renewal.
Managing the Cost of Fasenra Without Coverage
Fasenra is a treatment you stay on, so its real cost shows up over a year rather than in a single dose. That cost depends on your treatment, but even without insurance, help with the cost of Fasenra may be available for people who qualify.
Prescription Hope can handle that process for you, from the manufacturer’s application to each yearly renewal. When you’re ready, you can start your application to see whether you qualify.
FAQs About Fasenra Cost
Why Is Fasenra So Expensive?
Making a biologic like Fasenra takes a long, specialized process, and the medication has to be stored and shipped with care. No biosimilar version is available yet, so no lower-priced option competes with it.
Can You Get Fasenra at No Cost?
For people who qualify, Fasenra is provided at no cost by the manufacturer through a patient assistance program, but eligibility depends on household income and the manufacturer’s own guidelines, and the application process can be difficult to work through alone.
Prescription Hope is a prescription advocacy service that may be able to help you qualify. The service fee is $70 per month, per medication, and the team handles the application, the forms with your doctor, and the yearly renewals for you.
Can Prescription Hope Help If Your Insurance Won’t Cover Fasenra?
Yes, you can still apply, since Prescription Hope works alongside your current insurance even when the plan won’t cover Fasenra. After you apply, the team lets you know within 48 business hours whether you’re eligible.
Is Prescription Hope a Legitimate Service?
Prescription Hope has helped patients access brand-name medications since 2006. It is BBB accredited and LegitScript approved, and patient reviews are public on Google and Trustpilot.
