The Eliquis cost without insurance commonly runs around $459 at retail for a 30-day supply, though the manufacturer’s own list price and a couple of direct-pay options can bring that closer to $345-$350. Here’s where those numbers come from, and what actually lowers them.
How Much Does Eliquis Cost Without Insurance?
Bristol Myers Squibb and Pfizer, which make Eliquis, set the official list price (also called the wholesale acquisition cost) for a 30-day supply at $346. That’s the manufacturer’s baseline price before any pharmacy markup. At the pharmacy counter, cash prices tend to run higher than that baseline and can vary depending on:
- Pharmacy: Retail chains, warehouse clubs, and independent pharmacies each set their own cash price.
- Dosage and quantity: Eliquis comes in 2.5 mg and 5 mg tablets, and pricing can shift slightly by strength.
- Where you fill it: Cash prices can differ noticeably from one pharmacy to the next, even in the same area.
There’s no generic version of apixaban available at U.S. pharmacies yet. The FDA approved a generic back in 2019, but ongoing patent litigation is expected to keep it off pharmacy shelves until at least 2028. Until then, brand-name Eliquis remains the only option for most patients, which is part of why the price stays high.
How Far Discount Cards and Coupons Get You
A free GoodRx coupon currently brings the average cash price down to about $347.87 for a 30-day supply (60 tablets), a meaningful discount off GoodRx’s listed average retail price of $459.48. Comparing a few pharmacies before filling is worth the few minutes it takes, since cash prices can vary chain to chain.
That said, a coupon isn’t the only path for someone without insurance. Two other options, both run directly by the manufacturer, are worth knowing about.
The Manufacturer’s Direct-to-Patient Option: Eliquis 360 Support
Since September 2025, Bristol Myers Squibb and Pfizer have offered a direct-to-patient purchasing option built specifically for uninsured and self-paying patients. Through the Eliquis 360 Support program, eligible patients can order a 30-day supply (60 tablets) directly from the manufacturer for $345, shipped to their home in any of the 50 states or Puerto Rico.
A few things worth knowing about this option:
- It’s designed for people who are uninsured, have insurance that doesn’t cover Eliquis, or would pay less this way than through their commercial plan.
- Patients with Medicare Part D coverage are not eligible for this particular program; it’s built for the cash-pay and uninsured population specifically.
- You can start the process by calling 1-855-ELIQUIS (1-855-354-7847).
This makes it one of the more overlooked options for people paying out of pocket, since it isn’t a coupon or a discount card; it’s a standing cash price set directly by the manufacturer.
Why the Manufacturer’s Co-Pay Card Doesn’t Help If You’re Uninsured
Separately, Bristol Myers Squibb and Pfizer also offer a Co-Pay Card that can bring a commercially insured patient’s cost down to as little as $10 for a 30-day supply (or the first 90-day supply), with a $2,000 annual benefit cap. The catch: this card is explicitly restricted to patients who already have commercial insurance and a copay obligation for Eliquis. If you have no insurance at all, this particular card isn’t available to you; the discount card and direct-to-patient options above are the paths built for that situation instead.
The Eliquis Patient Assistance Program
The Bristol Myers Squibb Patient Assistance Foundation (BMSPAF) is an independent charitable organization that can provide Eliquis at no cost to patients who meet its criteria. In general, applicants need to:
- Live in the United States, Puerto Rico, or the U.S. Virgin Islands
- Be treated as an outpatient by a U.S.-licensed prescriber
- Have no insurance coverage for the medication
- Have a household income at or below roughly 300% of the federal poverty level (this threshold adjusts annually, so it’s worth confirming the current figure directly with the foundation)
Applications can be submitted at bmspaf.org, with your prescriber’s help. Processing typically takes a week or two once a complete application is received.
Between BMSPAF, the direct-to-patient program, and the Co-Pay Card, Bristol Myers Squibb and Pfizer run more assistance pathways than most manufacturers, but figuring out which one applies to your situation, and completing the paperwork, is exactly the kind of thing a prescription advocacy service is built to help with.
How Prescription Hope Fits In
Here’s what we are, plainly stated: Prescription Hope is not insurance, not a pharmacy, and not a coupon or discount card. We’re a patient advocacy service. We determine which manufacturer programs you may qualify for, complete and submit the applications, coordinate with your doctor’s office, manage refills, and handle annual renewals for a flat $70 per month, per medication service fee. The medications themselves are provided at no cost by the manufacturer.
We’ve done this since 2006, across more than 1,500 brand-name medications from over 180 manufacturers. We’re accredited by the Better Business Bureau. If you’d rather hear from patients than from us, our patient reviews are worth ten minutes.
Here’s what the process looks like: you complete a short enrollment form, an Enrollment Specialist calls to walk you through next steps, and our team coordinates the paperwork with your doctor’s office from there. Once approved, medication typically arrives within two to four weeks, usually as a 90-day supply shipped to your home or your doctor’s office. Eligibility depends on your income, your medication, and each manufacturer’s guidelines, so not everyone qualifies, but pre-qualification itself costs you nothing, and if we can’t help with a medication, you aren’t charged for it.
If Cost is a Barrier, Talk to Your Doctor
This section is for information only. Never stop, start, or change a medication without talking to your prescriber.
If Eliquis remains unaffordable even after exploring the options above, it’s worth having a direct conversation with your doctor about cost. They may know about assistance pathways patients don’t, and in some cases, may discuss whether another anticoagulant makes sense for your specific condition. Our comparison of Eliquis vs. Xarelto is a useful starting point for that conversation, though only your doctor can determine what’s clinically appropriate for you.
FAQs About the Cost of Eliquis Without Insurance
How much does Eliquis cost without insurance?
Cash prices average around $459 for a 30-day supply at retail. A GoodRx coupon brings that to about $348, and Bristol Myers Squibb’s own direct-to-patient program, Eliquis 360 Support, offers it for $345 a month to uninsured and self-paying patients.
Is there a generic for Eliquis?
Not yet. Generic apixaban received FDA approval in 2019, but ongoing patent litigation is expected to keep it off U.S. pharmacy shelves until at least 2028.
What is Eliquis 360 Support?
It’s a direct-to-patient purchasing program run by Bristol Myers Squibb and Pfizer for uninsured and self-paying patients, offering a 30-day supply for $345 shipped directly to your home. It’s not available to patients with Medicare Part D coverage.
Can I use the Eliquis Co-Pay Card if I don’t have insurance?
No. The Co-Pay Card is restricted to patients with commercial insurance and an existing copay obligation for Eliquis. Uninsured patients typically rely on a discount card, the direct-to-patient program, or the patient assistance program instead.
Can I get Eliquis at no cost through a patient assistance program?
Possibly. The Bristol Myers Squibb Patient Assistance Foundation provides Eliquis at no cost to patients who have no insurance coverage for it and meet its income guidelines. Our FAQ page covers how eligibility reviews generally work.
What if I still can’t afford Eliquis after all of this?
That’s a common place to land. Manufacturer assistance programs and prescription advocacy services exist for exactly this gap. Our guide on what to do when you can’t afford your medication walks through the remaining options.
Key Takeaways
- Without insurance, Eliquis costs around $459 a month at retail, with no generic available until at least 2028.
- A GoodRx coupon brings that down to about $348 a month.
- Bristol Myers Squibb’s Eliquis 360 Support direct-to-patient program offers a 30-day supply for $345 to uninsured and self-paying patients, but not to Medicare Part D patients.
- The manufacturer’s Co-Pay Card only helps commercially insured patients, not uninsured ones.
- The Bristol Myers Squibb Patient Assistance Foundation can provide Eliquis at no cost to income-qualified, uninsured patients.
- Prescription Hope is a patient advocacy service, not insurance, a pharmacy, or a discount card. We handle manufacturer program applications and ongoing management for a flat $70 monthly service fee per medication, and we’ve done it since 2006.
See what your monthly cost could look like. Start your application and find out if Eliquis qualifies for at-no-cost assistance through Prescription Hope.
