Taking CBD Oil With Melatonin, Dosage, Effects, and Safety

Posted March 31, 2021 by Michael Chamberlain - See Editorial Guidelines

Have you ever just laid in bed and stared at the ceiling for what seems like hours trying to go to sleep? You may be looking for supplements and methods for trying to get better sleep, making you question if you can take CBD oil with melatonin.

In this article, we’ll answer your questions regarding the use of CBD oil and melatonin, the dose, the potential effects, and compatibility. First, let’s start with a quick summary.

Can I take CBD oil with melatonin? CBD oil and melatonin are considered safe to take together. They have sleep benefits that complement each other, especially for insomnia. Take a 1-mg melatonin tablet, split it into two and take half each night. Combine with 10mg of CBD oil or take 0.25/0.50 mg for every one pound weight as a guide.

Keep this quick answer in mind as we get into more of the specifics and other considerations to take into account.

Medication tips

Taking CBD Oil With Melatonin

To begin with, the following is a brief explanation of available research and information. 

It’s important to clarify that both CBD oil and melatonin together can interact with other medications you may be taking. So, before following any of the proceeding information, we suggest you look to obtain your doctor’s consent.

The doses of either CBD oil or melatonin can vary if you’re taking them together for a night of better sleep.

In general, the dosage will depend on an array of factors such as age, weight, severity of insomnia, and other health conditions you may be experiencing. More on dosage shortly.

There is still no solid validity or reliability that taking CBD oil and melatonin together helps better sleep. So, only your doctor or relevant health professional can guide you on what’s good for you and your condition.

How CBD oil and melatonin work

In order to understand more about how these elements work together, let’s recap on both components.

Melatonin

Melatonin, in simple terms, is a hormone made by the pineal gland. It helps your body know when it’s time to sleep and wake up.

In other words, this hormone plays a crucial role in regulating your sleep-wake-up cycle, also known as the circadian rhythm

Normally, your body makes more melatonin at night. The production of this hormone starts after sunset and reduces in the morning. Being exposed to harsh light in the late evening or at night can block melatonin production.

The production of melatonin in the body is commonly affected by factors such as age and exposure to artificial light.

This is especially relevant to current generations as they are regularly exposed to artificial light through phones, tablets, and computers. Therefore, melatonin production is treating affected.

The result of having insufficient melatonin production is insomnia or other sleep-related problems.

This is why many people will use melatonin supplements to treat their sleep problems. 

These supplements work by activating the melatonin receptors in the brain, known as MT1 and MT2 receptors.

These receptors are the ones that inform or send signals to your brain that it’s time to sleep. Also, melatonin helps with the following as well:

  • Alleviating jet lag
  • Treating insomnia
  • Improving sleep efficiency and quality 
  • Minimizing the times you wake up during your sleep 
  • Reducing sleep latency
  • Balancing the sleep cycles for people who go through complete or partial blindness

CBD oil

CBD oil, also known as cannabidiol, is a non-psychoactive extract of the cannabis plant. It’s a supplement that’s recently becoming more popular.

CBD oil is commonly used to help with anxiety, stress, mood swings, immunity, appetite, digestion, metabolism, inflammatory responses, insomnia, other sleeping disorders, and different chronic pains.

CBD oil works by interacting with the endocannabinoid system (ECS) through cannabinoid receptors found all over the body.

There are two types of endocannabinoid receptors; CB-1 and CB-2:

  • CB-1 receptors are more active in the central nervous system
  • CB-2 receptors are more active in the immune system

The ECS regulates many vital bodily functions, which help in maintaining balance within the body.

It’s through these receptors and interactions that CBD oil appears to be able to affect many of the body’s functions, including your sleep-wake cycles. 

Connections between CBD oil and melatonin taken together

There is indeed a connection between CBD oil and melatonin.

Firstly, it’s that both have a strong positive impact on your sleep-wake cycle, especially helping with insomnia.

Secondly, the MT1 and MT2 melatonin receptors and CB-1 and CB-2 CBD receptors that influence sleep fall into the same group called G-protein coupled receptors.

This means they have a similar structure, process, and mechanism in which they influence the process of the sleep-wake cycle.

It’s this connection between CBD oil and melatonin that makes their benefits on sleep complement one other.

Is taking CBD oil with Melatonin safe?

Further research is necessary to validate this statement, but in general, both are safe to take together.

Both elements present naturally beneficial effects on sleep, so taking them together can be more effective, especially for insomnia.

But as we always advise, consult your doctor before making any changes.

To support this further, melatonin reverses hormonal disruption triggered by external factors supporting faster sleep.

On the other hand, CBD oil can help alleviate anxiety and stress symptoms, supporting a night of quality sleep.

As such, both CBD oil and melatonin combined can offer you a more sustained level of quality sleep, with minimal waking patterns.

The right dose for taking CBD oil with melatonin

Although taking both together is generally considered safe, make sure you don’t overload sleeping substances.

This can make your day inactive and drowsy. Your dose should help you with a quality sleep at night to make sure you are alert, active, productive, and happy during the day.

When it comes to finding the right dose for taking CDB oil with melatonin, start with the lowest dose possible. And as directed by your doctor, gradually increase your dose until you feel the balanced effects.

With that being said, below, we’ve added a short guide for each CBD oil and melatonin dose that can help you with safe dosing.

Melatonin dosage

Melatonin is often sold in standard doses of 1-milligram tablets. So you can use this standard dose and split it into two nights.

Cut the tablet into two and take one half each night. Even a small dose of 0.3 to 0.5 milligrams is still effective, depending on your condition.

Some may require doses such as 5 mg, but they may come with some side effects such as headaches, nausea, weird dreams, and wooziness. 

Now taking high doses of melatonin, especially anything higher than 5mg, is seen to be ineffective. So, taking a dose higher than 5mg will be unnecessary and is not worth the side effects. 

CBD Oil dosage

The effects of CBD oil for sleep or insomnia are heavily dependent on the dose.

When taken in small amounts, it may act as a stimulant. However, taking large doses can induce sedation.

This is why figuring out the right dose is important with CBD oil. 

The good news is that CBD has not been reported to have any adverse or fatal side effects. So, while you’re free to experiment, it’s advisory to keep it moderate as it can and does show mild side effects. 

10 mg of CBD oil is a good starting point. Low doses of CBD oil can provide stimulating effects. As a general rule, consider 0.25 mg for every one pound of body weight. So, for an average 200-pound adult, 50 mg would be a guideline dose.

If you need a stronger dose, then consider 0.5 mg for every one pound of body weight. So again, for a 200-pound adult, that would be a dose of 100 mg to experience stronger effects.

Closing thoughts

We hope this has provided you with an overview of whether to take CBD oil with melatonin. As always, consult your doctor before making any potentially significant changes to your medications.



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