What is an Artificial Pancreas – Who Makes it and the Cost
Posted by Prescription Hope - See Editorial Guidelines (Last Updated On: Fri Apr 28 2023)
An artificial pancreas may sound fancier than what it really is, but it can be extremely helpful for those with type 1 diabetes. In this article, we will cover how the artificial pancreas mimics the actual pancreas, who makes these systems, and how much they cost. Before we dive in too much, here’s a quick overview: An artificial pancreas may also be called a bionic pancreas, closed-loop insulin pump, or an automated insulin delivery system. There are a few major companies developing and perfecting the system. Those with type 1 diabetes can use an artificial pancreas to better control glucose levels and worry less. First, we must cover what the pancreas is and how it works before understanding the details of an artificial pancreas.
How the Pancreas Works
![Artificial Pancreas](https://prescriptionhope.com/wp-content/uploads/2020/01/What-is-an-Artificial-Pancreas-1024x1024.jpg)
Exocrine
Essentially, the exocrine system is responsible for producing enzymes that carry substances outside the body. This system is crucial for helping digest and breakdown foods. The pancreas has more than just one responsible when it comes to the exocrine system. The first being the production of bicarbonate. The bicarbonate secretion aids in removing stomach acid, which is vital for the digestive process. The pancreas will also produce a few different enzymes, with each having its own job.- Proteases – This is an enzyme that breaks protein down into amino acids.
- Lipase – This enzyme is responsible for breaking down fats.
- Amylase – This one is responsible for breaking down carbohydrates.
Endocrine
When it comes to relating the artificial pancreas to the real pancreas, the endocrine system is where the majority of the similarities lie. Those with diabetes are dealing mostly with the endocrine system, because of the hormones known as insulin and glucagon. When you eat, your blood sugar will begin to rise. A working and healthy pancreas will sense this rise in glucose and begin releasing insulin into the bloodstream. Insulin is what transports the glucose into cells. Some cells will use this for energy, and other cells will store the glucose. Glucagon is the hormone that triggers your liver to produce glucose. When glucagon kicks in, your liver will take stored glycogen and turn it into glucose to be released into the bloodstream. The pancreas releases glucagon when it senses your blood sugar getting below the normal level. Now that you understand the functions of the pancreas, it’s time to discuss how an artificial pancreas can works.How the Artificial Pancreas Imitates the Real Thing
When you first hear “artificial pancreas” or “bionic pancreas,” you might be thinking of some 3D printed device that gets implanted into your body. That may become something in the future, but that’s not exactly what we are talking about here. As mentioned at the beginning of this article, an artificial pancreas can also be called a closed-loop system.![Artificial Pancreas](https://prescriptionhope.com/wp-content/uploads/2020/01/What-is-an-Artificial-Pancreas-2-1024x683.jpg)
Who Manufactures an Artificial Pancreas
There are a few major manufacturers that have an artificial pancreas, or a closed-loop insulin pump, out currently. The makers of these products are continually seeking new ways to innovate and improve their products. So, keep in mind that as time goes on, new companies may enter this space and technologies will improve.Medtronic
Medtronic is one of the first companies to produce an automated insulin delivery system. In 2016 Medtronic received approval from the FDA for its closed-loop insulin pump called MiniMed 670G. The current continuous glucose sensor that is used for the closed-loop system is known as the Guardian 3. As of right now, the sensor has to be used along with finger sticks to ensure accuracy. However, Medtronic is looking to get approval from the FDA for non-adjunctive labeling, which would make the sensor available to those with Medicare. What this means is that the sensor would be approved to be used alone and without finger sticks.Tandem Diabetes Care
Tandem Diabetes Care also has a closed-loop insulin pump, known as Control-IQ. This system utilizes a Dexcom CGM and the t:slim X2 insulin pump. The Dexcom CGM has been proven to read blood sugar levels accurately and works to predict blood sugar levels up to 30 minutes ahead of time. This allows the insulin delivery system to make adjustments and calculations, thus preventing hyper and hypoglycemia. This system has been approved by the FDA in 2019 and has started shipping throughout the U.S as of late January 2020. Another positive with the Tandem artificial pancreas is that it allows the user to override the system and manual deliver insulin.Insulet Corporation
Insulet Corporation is the manufacturer of the popular tubeless insulin pump known as Omnipod. Though the Omnipod is tubeless, it does need to be changed every three days. Insulet is working on an artificial pancreas system that will utilize the Omnipod insulin pump as well as the Dexcom CGM. They will also use an algorithm, created by Mode AGC (Automated Glucose Control LLC), in the system to help calculate insulin delivery. The system will be called Omnipod Horizon. This artificial pancreas underwent an early-stage study between 2016 and 2017. A secondary study to determine accuracy and performance was done in early 2019. Insulet Corporation has not stated a release date for this system.Future of the Artificial Pancreas
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Costs
An artificial pancreas cost will vary from individual to individual, as it depends on the type of insurance one has. However, there have been estimates made for what it would cost to get one of these closed-loop insulin pumps. For an artificial pancreas from Medtronic, you may expect to pay somewhere in the range of 5,000-8,000 dollars. The price may go up from there depending on how many glucose sensors the individual goes through in a year. Keep in mind that with these systems, insulin is still needed. The system does not come with insulin. Needless to say, proper management of diabetes is pricey and burdensome. This is why Prescription Hope’s medication access service exists. Get your insulin for a set, affordable costs every month.Conclusion
We hope that this information has given you greater insight into therapies for those contending with diabetes. Diabetes can be a relentless illness that places a financial burden on the individual and families. Prescription Hope can help you afford your insulin or other medication for a set costs of $60.00 a month through Prescription Hope’s medication access service for each medication. Enroll with us to determine if you are eligible.What is the difference between an artificial pancreas and insulin pump?
An insulin pump only delivers insulin through a preset basal rate and with a manually calculated bolus. Whereas, an artificial pancreas works with a continuous glucose monitor to determine how much insulin a patient needs, creating a closed-loop system.